Can P Force Extra Super Be Taken With Antifungal Medications?
P Force Extra Super is a combination medication containing Sildenafil Citrate (100 mg) for treating erectile dysfunction (ED) and Dapoxetine (60 mg) for managing premature ejaculation (PE). While this dual-action formula is effective, it must be used with caution—especially when taken with antifungal medications.
Many antifungal drugs, such as ketoconazole, itraconazole, fluconazole, and voriconazole, are known CYP3A4 enzyme inhibitors. These enzymes are responsible for breaking down Sildenafil in the liver. When antifungals block this enzyme, Sildenafil can build up in the bloodstream, leading to stronger and longer-lasting effects, and increasing the risk of side effects like low blood pressure, headache, flushing, dizziness, and priapism (a prolonged, painful erection).
Additionally, antifungals may also interfere with Dapoxetine metabolism, potentially increasing central nervous system side effects like nausea, anxiety, and dizziness.
Important Advice:
Do not combine P Force Extra Super with systemic antifungal medications without consulting a doctor.
If antifungal treatment is essential, your doctor may adjust the dose of P Force Extra Super or recommend an alternative ED treatment with a safer interaction profile.
Taking P Force Extra Super with antifungal medications can lead to dangerous drug interactions. Always consult a healthcare provider before combining them.  |